منابع مشابه
Community gene annotation in practice
Manual annotation of genomic data is extremely valuable to produce an accurate reference gene set but is expensive compared with automatic methods and so has been limited to model organisms. Annotation tools that have been developed at the Wellcome Trust Sanger Institute (WTSI, http://www.sanger.ac.uk/.) are being used to fill that gap, as they can be used remotely and so open up viable communi...
متن کاملDetecting Community Structures in Gene Networks using Gene-Ontology Annotation
Abstract In this note, we explore — by means of a specific case study — the potential of a new approach towards identifying gene functional modules in Gene-Ontology (or, for short, GO) networks, i.e., networks whose nodes are formed by the genes from a given collection of genes under consideration while two such nodes are connected by an edge if and only if they share — according to their GO an...
متن کاملThe Gene Wiki: community intelligence applied to human gene annotation
Annotating the function of all human genes is a critical, yet formidable, challenge. Current gene annotation efforts focus on centralized curation resources, but it is increasingly clear that this approach does not scale with the rapid growth of the biomedical literature. The Gene Wiki utilizes an alternative and complementary model based on the principle of community intelligence. Directly int...
متن کاملA Gene Wiki for Community Annotation of Gene Function
Community Page G ene portals (e.g., Entrez Gene [1] and Ensembl [2]) and model organism databases (e.g., Mouse Genome Database [3], Rat Genome Database [4], FlyBase [5]) are popular and useful tools for researching gene annotation and enforcing data standards. These databases provide a large volume and diversity of information on each gene, including protein and transcript sequences, genome loc...
متن کاملThe Gene Wiki in 2011: community intelligence applied to human gene annotation
The Gene Wiki is an open-access and openly editable collection of Wikipedia articles about human genes. Initiated in 2008, it has grown to include articles about more than 10,000 genes that, collectively, contain more than 1.4 million words of gene-centric text with extensive citations back to the primary scientific literature. This growing body of useful, gene-centric content is the result of ...
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ژورنال
عنوان ژورنال: Database
سال: 2012
ISSN: 1758-0463
DOI: 10.1093/database/bas009